Carol Shakir,Mahasin Alias,Emad Yousif: Rd Cell Line Study of New Complexes of Some Transition Metals

Rd Cell Line Study of New Complexes of Some Transition Metals


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A new ligand of dithiocarbamato derivative containing triazole ring and hydrazide group in it, have been synthesized in this work. The product was isolated, characterized, and studied by appropriate physical measurements i.e. FT-IR, UV-Vis spectroscopy and the elemental analysis C.H.N.S as well as melting point. The new ligand was used to prepare a number of transition metal complexes (heavy and light metals). Cytotoxicity effect of some complexes (heavy metals) (PtL, AuL, RhL, CuL & PdL) as well as ligand have evaluated against RD cell line by using four different concentrations (500, 250, 125& 62.5 g/ml) respectively, and in three exposure times 24, 48 and 72 hrs and compared this cytotoxic effect with control positive Cis-Pt, the results showed the cytotoxic effects of new compounds on RD cell line depending on both concentration and time of exposure.

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Author: Carol Shakir,Mahasin Alias,Emad Yousif
Number of Pages: 144 pages
Published Date: 01 Jun 2012
Publisher: LAP Lambert Academic Publishing
Publication Country: Saarbrucken, Germany
Language: English
ISBN: 9783659142314
Download Link: Click Here
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